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Rebastinib, MedChemExpress

Product Code. 16461667
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Product Code. 16461667 Supplier Medchem Express Supplier No. HY13024

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Description

MedChemExpress Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1WT and Abl1T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit.

Rebastinib (DCC-2036) is an orally active, non-ATP-competitive Bcr-Abl inhibitor for Abl1WT and Abl1T315I with IC50s of 0.8 nM and 4 nM, respectively. Rebastinib also inhibits SRC, KDR, FLT3, and Tie-2, and has low activity to seen towards c-Kit.

Specifications

Chemical Name or Material Rebastinib
CAS 1020172-07-9
Color Off-White
Purity Grade Notes Research
Molecular Formula C30H28FN7O3
Quantity 50 mg
Synonym DCC-2036
Solubility Information DMSO : 50 mg/mL (90.32 mM; ultrasonic and warming and heat to 80°C)
SMILES CC(C)(C)C1=NN(C(NC(NC2=C(F)C=C(OC3=CC(C(NC)=O)=NC=C3)C=C2)=O)=C1)C4=CC=C5C(C=CC=N5)=C4
Molecular Weight (g/mol) 553.59
Formula Weight 553.59
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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