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Tocris Bioscience™ MK6-83

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
MK6-83 is a TRPML channel activator (EC50 = 110 nM). Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively). Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.
Specifications
Specifications
| Chemical Name or Material | MK6-83 |
| CAS | 1062271-24-2 |
| Synonym | 5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide |
| Quantity | 10 mg |
| Solubility | Soluble to 100mM in DMSO and to 20mM in ethanol |
| Molecular Formula | C16H20N2O2S2 |
| Formula Weight | 336.47 |
| Physical Form | Solid |
| Product Type | Bioactive Small Molecule |
| Purity | >98% |
Research Use Only. Not For Human or Veterinary Use
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