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Prinaberel, MedChemExpress

Product Code. 16462387
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Product Code. 16462387 Supplier Medchem Express Supplier No. HY14933

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Description

MedChemExpress Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis.

Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis.

Specifications

Chemical Name or Material Prinaberel
CAS 524684-52-4
Color Light Gray
Purity Grade Notes Research
Molecular Formula C15H10FNO3
Quantity 50 mg
Synonym ERB-041
Solubility Information DMSO : ≥ 40 mg/mL (147.47 mM)
SMILES OC1=CC(C=C)=C(OC(C2=CC=C(O)C(F)=C2)=N3)C3=C1
Molecular Weight (g/mol) 271.24
Formula Weight 271.24
Percent Purity 98.05%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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