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Ponatinib, MedChemExpress

Product Code. 16494948
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Product Code. 16494948 Supplier Medchem Express Supplier No. HY12047

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Description

MedChemExpress Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

Ponatinib (AP24534) is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM, and 5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively.

Specifications

Chemical Name or Material Ponatinib
Physical Form Solid
CAS 943319-70-8
Color Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C29H27F3N6O
For Use With (Application) Cancer-Kinase/protease
Synonym AP24534
Solubility Information DMSO : 50 mg/mL (93.89 mM; Need ultrasonic)
SMILES CC1=C(C=C(C=C1)C(NC2=CC(C(F)(F)F)=C(C=C2)CN3CCN(CC3)C)=O)C#CC4=CN=C5N4N=CC=C5
Molecular Weight (g/mol) 532.56
Formula Weight 532.56
Percent Purity 97.56%
Grade Research
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Research purposes only

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