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PNU-159682, MedChemExpress
Description
PNU-159682, a metabolite of the anthracycline Nemorubicin, is a highly potent DNA topoisomerase II inhibitor with excellent cytotoxicity. PNU-159682 acts as a more potent and tolerated ADC cytotoxin than Doxorubicin for ADC synthesis. PNU-159682 can be used in EDV-nanocell technology to overcome drug resistance.
Specifications
Specifications
| Chemical Name or Material | PNU-159682 |
| CAS | 202350-68-3 |
| Color | Reddish Brown |
| Purity Grade Notes | Research |
| Molecular Formula | C32H35NO13 |
| Quantity | 10 mg |
| Solubility Information | DMSO : 100 mg/mL (155.86 mM; Need ultrasonic) |
| SMILES | COC1=C(C(C(C(O)=C([C@@H](O[C@H]2C[C@H]3[C@H](O[C@H]4N3CCO[C@@H]4OC)[C@H](C)O2)C[C@@](C(CO)=O)(O)C5)C5=C6O)=C6C7=O)=O)C7=CC=C1 |
| Molecular Weight (g/mol) | 641.62 |
| Formula Weight | 641.62 |
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Research purposes only
Product Title
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