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Plinabulin, MedChemExpress

Product Code. 16496068
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Product Code. 16496068 Supplier Medchem Express Supplier No. HY14444

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Description

MedChemExpress Plinabulin (NPI-2358) is a vascular disrupting agen (VDA) against tubulin-depolymerizing with an IC50 of 9.8 nM against HT-29 cells. Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells.

Plinabulin (NPI-2358) is a vascular disrupting agen (VDA) against tubulin-depolymerizing with an IC50 of 9.8 nM against HT-29 cells. Plinabulin binds the colchicine binding site of β-tubulin preventing polymerization and has potent inhibitory to tumor cells.

Specifications

Chemical Name or Material Plinabulin
CAS 714272-27-2
Color Yellow
Purity Grade Notes Research
Molecular Formula C19H20N4O2
Quantity 10 mg
Synonym NPI-2358
Solubility Information DMSO : 50 mg/mL (148.64 mM; Need ultrasonic)
SMILES O=C(N/C1=C\C2=C(NC=N2)C(C)(C)C)/C(NC1=O)=C/C3=CC=CC=C3
Molecular Weight (g/mol) 336.39
Formula Weight 336.39
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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