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Thermo Scientific™ SPB (succinimidyl-[4-(psoralen-8-yloxy)]-butyrate)

Product Code. 10627534 Shop All Thermo Scientific Products
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Quantity:
50 mg
Unit Size:
50mg
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Product Code. 10627534

Brand: Thermo Scientific™ 23013

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Description

Crosslink amines to DNA with this crosslinker composed of NHS-ester and psoralen reactive groups; conjugates to DNA via light-activated intercalation next to pyrimidine bases.

Thermo Scientific™ Pierce SPB is an NHS-ester and psoralen crosslinker that effectively conjugates primary amines to DNA via light-activated intercalation next to pyrimidine bases.

Highlights:

  • Melting point: 177-178°C
  • Reactive groups: NHS ester and psoralen (Amax= 282nm)
  • Reactive toward: amino groups pyrimidines in DNA or RNA
TRUSTED_SUSTAINABILITY

Specifications

Chemical Reactivity Amine-Nonselective
Cleavable No
Description SPB
Molecular Weight (g/mol) 385.32
PEGylated No
Spacer Arm Length 8.6 Å
Content And Storage Upon receipt store desiccated at 4°C.
Cell Permeability Not determined
Shipping Condition Ambient
Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Heterobifunctional
Reactive Moiety Psoralen, NHS Ester
Spacer Short (<10 Å)
Form Solid
Quantity 50 mg
Solubility DMF, DMSO
Format Standard
Water Soluble No
Product Type Crosslinker
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For Research Use Only. Not for use in diagnostic procedures.

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