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PD146176, MedChemExpress
Description
PD146176 (NSC168807), a 15-Lipoxygenase (15-LO) inhibitor, inhibits rabbit reticulocyte 15-LO (Ki=197 nM, IC50=0.54 μM). PD146176 reverses cognitive impairment, brain amyloidosis, and tau pathology by stimulating autophagy in aged triple transgenic mice.
Specifications
Specifications
| Chemical Name or Material | PD146176 |
| CAS | 4079-26-9 |
| Color | Brown |
| Purity Grade Notes | Research |
| Molecular Formula | C15H11NS |
| Quantity | 5 mg |
| Synonym | NSC168807 |
| Solubility Information | DMSO : 25 mg/mL (105.34 mM; Need ultrasonic) |
| SMILES | C1(N2)=C(CSC3=CC=CC=C31)C4=C2C=CC=C4 |
| Molecular Weight (g/mol) | 237.32 |
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Research purposes only
Product Title
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