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Tocris Bioscience™ PD 98059
GREENER_CHOICE

MEK inhibitor

Brand:  Tocris Bioscience™ 1213/10

Encompass

Product Code. 13498893

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Description

Description

PD 98059 is an inhibitor of mitogen-activated protein kinase kinase (MKK/ MEK). Acts by binding to the inactivated form of MEK, thereby preventing its phosphorylation by cRAF or MEK kinase (IC50 = 2-7 μM). Inhibits cell growth and proliferation in acute myelogenous leukemia (AML) cell lines; causes G1 arrest by blocking p53-dependent p21 induction. Enhances embryonic stem cell self-renewal.
Specifications

Specifications

98%
167869-21-8
10 mg
2-(2-Amino-3-methoxyphenyl)-4 H-1-benzopyran-4-one
Room Temperature
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