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  7. Palbociclib isethionate, MedChemExpress

Palbociclib isethionate, MedChemExpress

Product Code. 16461976
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Product Code. 16461976 Supplier Medchem Express Supplier No. HYA0065

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Description

MedChemExpress Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Palbociclib (PD 0332991) isethionate is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib isethionate has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma.

Specifications

Chemical Name or Material Palbociclib isethionate
CAS 827022-33-3
Color Yellow
Purity Grade Notes Research
Molecular Formula C26H35N7O6S
Quantity 500 mg
Synonym PD 0332991 isethionate
Solubility Information H2O : 50 mg/mL (87.16 mM; Need ultrasonic) ∣DMSO : 10 mg/mL (17.43 mM; Need ultrasonic)
SMILES CC(C1=C(N2C3CCCC3)N=C(NC4=NC=C(N5CCNCC5)C=C4)N=C1)=C(C(C)=O)C2=O.OCCS(O)(=O)=O
Molecular Weight (g/mol) 573.66
Formula Weight 573.66
Percent Purity 99.52%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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