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Orotic acid, MedChemExpress

Product Code. 16489006
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Product Code. 16489006 Supplier Medchem Express Supplier No. HYN0157

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Description

MedChemExpress Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats.

Orotic acid (6-Carboxyuracil), a precursor in biosynthesis of pyrimidine nucleotides and RNA, is released from the mitochondrial dihydroorotate dehydrogenase (DHODH) for conversion to UMP by the cytoplasmic UMP synthase enzyme. Orotic acid is a marker for measurement in routine newborn screening for urea cycle disorders. Orotic acid can induce hepatic steatosis and hepatomegaly in rats.

Specifications

Chemical Name or Material Orotic acid
CAS 65-86-1
Color White
Purity Grade Notes Research
Molecular Formula C5H4N2O4
Quantity 100 mg
Synonym 6-Carboxyuracil Vitamin B13
Solubility Information DMSO : 55 mg/mL (352.34 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(C(NC1=O)=CC(N1)=O)O
Molecular Weight (g/mol) 156.1
Formula Weight 156.1
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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