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Oglemilast, MedChemExpress

Product Code. 16492457
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Product Code. 16492457 Supplier Medchem Express Supplier No. HY15178

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Description

MedChemExpress Oglemilast (GRC 3886) is a potent and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 0.5 nM for PDE4D3. Oglemilast inhibits pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast has the potential for inflammatory airway diseases.

Oglemilast (GRC 3886) is a potent and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 0.5 nM for PDE4D3. Oglemilast inhibits pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast has the potential for inflammatory airway diseases.

Specifications

Chemical Name or Material Oglemilast
CAS 778576-62-8
Color Khaki
Purity Grade Notes Research
Molecular Formula C20H13Cl2F2N3O5S
Quantity 50 mg
Synonym GRC 3886
Solubility Information DMSO : 4 mg/mL (7.75 mM; Need ultrasonic)
SMILES O=C(C1=C2C(OC3=CC=C(NS(=O)(C)=O)C=C23)=C(OC(F)F)C=C1)NC4=C(Cl)C=NC=C4Cl
Molecular Weight (g/mol) 516.3
Formula Weight 516.3
Percent Purity 98.2%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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