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Invitrogen™ OBFC1 Polyclonal Antibody

Description
Immunogen sequence: PVFLAFAKLY IRDILDMKES RQVPGVFLYN GHPIKQVDVL GTVIGVRERD AFYSYGVDDS TGVINCICWK KLNTESVSAA PSAARELSLT SQLKKLQETI EQKTKI Highest antigen sequence indentity to the following orthologs: Mouse - 72%, Rat - 71%.
OBFC1 is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
Specifications
Specifications
| Antigen | OBFC1 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | STN1 |
| Gene Accession No. | Q9H668 |
| Gene Alias | 0610009H20Rik; 2310057J23Rik; AAF44; AAF-44; AI413458; alpha accessory factor 44; alpha-accessory factor of 44 kDa; bA541N10.2; CST complex subunit STN1; Obfc1; oligonucleotide/oligosaccharide binding fold containing 1; oligonucleotide/oligosaccharide-binding fold containing 1; oligonucleotide/oligosaccharide-binding fold-containing protein 1; replication protein A 32 kDa subunit; RPA-32; STN1; STN1 subunit of CST complex; STN1, CST complex subunit; suppressor of cdc thirteen homolog |
| Gene Symbols | STN1 |
| Show More |
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