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Tocris Bioscience™ Obatoclax Mesylate
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Product Code. 18729226
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Product Code. 18729226 Supplier Tocris Bioscience™ Supplier No. 6539/10

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Description

Inhibitor of Bcl-2 family members (IC50 values are 1.11 - 7 μM); antiapoptotic

Obatoclax mesylate is an inhibitor of Bcl-2 family members (IC50 values are 1.11 - 7 μM). Inhibits the interaction of a BH3 domain peptide with 6 members of the Bcl-2 family (Bcl-2, Bcl-XL, Mcl-1, Bcl-W, A1, and Bcl-B) in vitro. Has antiapoptotic and antitumor effects in several tumor bearing mouse models.
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Specifications

Chemical Name or Material 2-[2-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene)-3-methoxy-2H-pyrrol-5-yl]-1H-indole methanesulfonate
CAS 803712-79-0
Synonym GX15-070
Quantity 10 mg
Molecular Formula C20H19N3O.CH3SO3H
Formula Weight 413.49
Purity 98%
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