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NVP-ADW742, MedChemExpress

Product Code. p-200097128
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Product Code. 16486467 Supplier Medchem Express Supplier No. HY10252

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Description

MedChemExpress NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.

NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.

Specifications

Chemical Name or Material NVP-ADW742
CAS 475488-23-4
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C28H31N5O
Quantity 5 mg
Synonym ADW742 GSK 552602A ADW
Solubility Information DMSO : 19.23 mg/mL (42.40 mM; Need ultrasonic)
SMILES NC1=C2C(N(C=C2C3=CC=CC(OCC4=CC=CC=C4)=C3)[C@H]5C[C@@H](C5)CN6CCCC6)=NC=N1
Molecular Weight (g/mol) 453.58
Formula Weight 453.58
Percent Purity 98.31%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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