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Invitrogen™ NR5A1 Polyclonal Antibody
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Product Code. 13464619
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Quantity:
50 μg
Unit Size:
50µg
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13464619 50 μg 50µg
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Product Code. 13464619 Supplier Invitrogen™ Supplier No. PA532950

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Description

Rabbit Polyclonal Antibody

Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Elephant, Rabbit, Opossum (94%); Panda, Horse, Pig, Turkey, Chicken (88%); Platypus (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Steroidogenic factor-1 (SF-1) is an orphan nuclear receptor involved in organ development and differentiation of the endocrine system. SF-1 has been shown to be essential for fetal development of the hypothalamus, pituitary gland, gonads, and the adrenal gland. SF-1 has been shown to promote transcriptional activity of many steroidogenic enzymes from the cytochrome P450 family. SF-1 contains two activation function domains, designated AF1 and AF2, common to many nuclear steroid receptors which have been shown to be necessary for interaction with other nuclear receptors as well as coactivators and corepressors including steroid receptor coactivator-1 (SRC-1), glucocorticoid receptor interacting protein 1 (GRIP1), cAMP response element binding protein (CREB) binding protein (CBP) and silencing mediator of retinoid acid and thyroid hormone receptor (SMRT).
TRUSTED_SUSTAINABILITY

Specifications

Antigen NR5A1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.7 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene Nr5a1
Gene Accession No. Q13285
Gene Alias Ad4BP; Ad4BP/SF-1; adrenal 4 binding protein; Adrenal 4 binding protein (AD4BP); adrenal 4-binding protein; ELP; ELP-3; Embryonal long terminal repeat-binding protein; embryonal LTR-binding protein; FTZ1; FTZF1; Ftz-F1; fushi tarazu 1 factor homolog; fushi tarazu factor homolog 1; Fushi tarazu factor homolog 1 (FTZ1); hSF-1; Nr5a1; nuclear receptor AdBP4; nuclear receptor subfamily 5 group A member 1; Nuclear receptor subfamily 5 group A member 1 (NR5A1); nuclear receptor subfamily 5, group A, member 1; POF7; SF1; SF-1; SPGF8; SRXY3; Steroid hormone receptor Ad4BP; steroid hydroxylase positive regulator; Steroidogenic factor 1; Steroidogenic factor 1 (SF1); steroidogenic factor 1 nuclear receptor; steroidogenic factor-1; STF1; STF-1
Gene Symbols Nr5a1
Host Species Rabbit
Immunogen Synthetic 17 amino acid peptide from near C-terminus of human NR5A1.
Purification Method Antigen affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2516
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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