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Nitrendipine

Product Code. 15463549
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Product Code. 15463549 Supplier Thermo Scientific Alfa Aesar Supplier No. J60841.MC
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Estimated Shipment: 11-12-2026
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Description

L-type calcium channel blocker | CAS: 39562-70-4 | C18H20N2O6 | 360.366 g/mol

Nitrendipine modulates NMDA receptor channel function in mammalian neurons. Nitrendipine has been shown to inhibit neutrophil adhesion to vascular endothelium. It is used in the treatment of primary hypertension to decrease blood pressure. Nitrendipine is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in DMSO (17.5 mg/ml), methanol (15 mg/ml), ethyl acetate, and ethanol (25 mM). Insoluble in water.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 39562-70-4
Molecular Formula C18H20N2O6
Molecular Weight (g/mol) 360.366
MDL Number MFCD00082255
InChI Key PVHUJELLJLJGLN-UHFFFAOYSA-N
Synonym nitrendipine, bayotensin, baypress, nidrel, nitrendipinum, nitrendipino, bylotensin, nitrendipin, deiten, nitrepin
PubChem CID 4507
ChEBI CHEBI:7582
IUPAC Name 5-O-ethyl 3-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES CCOC(=O)C1=C(NC(=C(C1C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OC)C)C

Specifications

Color Yellow to Green
Quantity 100 mg
Merck Index 14,6576
Solubility Information Soluble in DMSO (17.5mg/ml),methanol (15mg/ml),ethyl acetate,and ethanol (25 mM). Insoluble in water.
Formula Weight 360.36
Physical Form Powder
Chemical Name or Material Nitrendipine

RUO – Research Use Only

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