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Niraparib, MedChemExpress

Product Code. 16465046
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Product Code. 16465046 Supplier Medchem Express Supplier No. HY10619

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Description

MedChemExpress Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Niraparib (MK-4827) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Specifications

Chemical Name or Material Niraparib
CAS 1038915-60-4
Color Off-White
Purity Grade Notes Research
Molecular Formula C19H20N4O
Quantity 100 mg
Synonym MK-4827
Solubility Information DMSO : 25 mg/mL (78.03 mM; Need ultrasonic)
SMILES NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O
Molecular Weight (g/mol) 320.39
Formula Weight 320.39
Percent Purity 98.13%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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