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Niraparib hydrochloride, MedChemExpress

Product Code. 16475046
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Product Code. 16475046 Supplier Medchem Express Supplier No. HY10619A

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Description

MedChemExpress Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC50s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Specifications

Chemical Name or Material Niraparib hydrochloride
CAS 1038915-64-8
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C19H21ClN4O
Quantity 100 mg
Synonym MK-4827 hydrochloride
Solubility Information DMSO : 250 mg/mL (700.57 mM; Need ultrasonic) ∣H2O : 100 mg/mL (280.23 mM; Need ultrasonic)
SMILES NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.Cl
Molecular Weight (g/mol) 356.85
Formula Weight 356.85
Percent Purity 99.76%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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