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Neratinib, MedChemExpress

Product Code. 16471306
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Product Code. 16471306

Brand: Medchem Express HY32721

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Description

MedChemExpress Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively.

Neratinib (HKI-272) is an orally available, irreversible, highly selective HER2 and EGFR inhibitor with IC50s of 59 nM and 92 nM, respectively.

Specifications

Chemical Name or Material Neratinib
CAS 698387-09-6
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C30H29ClN6O3
Quantity 200 mg
Synonym HKI-272
Solubility Information DMSO : 13.33 mg/mL (23.93 mM; Need ultrasonic)
SMILES ClC1=C(OCC2=NC=CC=C2)C=CC(NC3=C(C#N)C=NC4=CC(OCC)=C(NC(/C=C/CN(C)C)=O)C=C43)=C1
Molecular Weight (g/mol) 557.04
Formula Weight 557.04
Percent Purity 96.08%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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