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Naloxone hydrochloride, 98%

Product Code. 15462859
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Product Code. 15462859 Supplier Thermo Scientific Alfa Aesar Supplier No. J60013.ME
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Description

Naloxone hydrochloride, CAS # 357-08-4, is involved in the blockade of the mu-opioid receptor and removal of other compounds from the receptor site. | CAS: 357-08-4 | C19H22ClNO4 | 363.838 g/mol

A specific opiate antagonist. Blocks the action of sigma-agonists at opioid sites.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Naloxone hydrochloride the hydrochloride salt of the anti-opioid naloxone

Application

  • Naloxone is a fast-acting inverse agonist of the mu-opioid receptor that can be used to competitively inhibit the binding of opioid compounds
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 357-08-4
Molecular Formula C19H22ClNO4
Molecular Weight (g/mol) 363.838
MDL Number MFCD00069322
InChI Key RGPDIGOSVORSAK-STHHAXOLSA-N
Synonym naloxone hydrochloride, naloxone hcl, narcan, evzio, unii-f850569pqr, nalonee, 17-allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride, narcan tn, naloxonehydrochloride
PubChem CID 5464092
IUPAC Name (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
SMILES C=CCN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)O)O4)O.Cl

Specifications

Melting Point 200°C to 205°C
Color White
Quantity 500 mg
Merck Index 14,6362
Solubility Information Soluble in water (73mg/ml),ethanol (3.3mg/ml),methanol (50mg/ml) and dimethyl sulfoxide (73mg/ml). Insoluble in ether
Formula Weight 363.84
Percent Purity 98%
Physical Form Crystalline Powder
Chemical Name or Material Naloxone hydrochloride

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