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N-Desmethylclozapine, MedChemExpress

Product Code. 16498798
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Product Code. 16498798 Supplier Medchem Express Supplier No. HYG0021
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Estimated Shipment: 07-08-2026
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Description

MedChemExpress N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist.

N-Desmethylclozapine is a major active metabolite of the atypical antipsychotic drug Clozapine. N-Desmethylclozapine is a potent, allosteric and partial M1 receptors agonist (EC50=115 nM) and is able to potentiate hippocampal N-methyl-d-aspartate (NMDA) receptor currents through M1 receptor activation. N-Desmethylclozapine is also a δ-opioid agonist.

Spécification

Chemical Name or Material N-Desmethylclozapine
CAS 6104-71-8
Color Yellow
Purity Grade Notes Research
Molecular Formula C17H17ClN4
Quantity 10 mg
Synonym Norclozapine Desmethylclozapine Normethylclozapine
Solubility Information DMSO : ≥ 50 mg/mL (159.85 mM)
SMILES ClC1=CC=C2C(N=C(N3CCNCC3)C4=CC=CC=C4N2)=C1
Molecular Weight (g/mol) 312.8
Formula Weight 312.8
Percent Purity 99.66%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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