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MNS, MedChemExpress

Product Code. 16481956
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Product Code. 16481956 Supplier Medchem Express Supplier No. HY78263

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Description

MedChemExpress MNS (NSC 170724), the beta-nitrostyrene derivative, is a potent tyrosine kinase inhibitor and a broad-spectrum antiplatelet agent. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 μM, respectively. MNS inhibits Src, Syk, and FAK with IC50 of 27.3, 2.8, and 97.6 μM, respectively.

MNS (NSC 170724), the beta-nitrostyrene derivative, is a potent tyrosine kinase inhibitor and a broad-spectrum antiplatelet agent. MNS completely inhibits U46619, ADP-, arachidonic acid-, collagen-, and thrombin-induced platelet aggregation with IC50 values of 2.1, 4.1, 5.8, 7.0, and 12.7 μM, respectively. MNS inhibits Src, Syk, and FAK with IC50 of 27.3, 2.8, and 97.6 μM, respectively.

Specifications

Chemical Name or Material MNS
CAS 1485-00-3
Color Deep Yellow
Purity Grade Notes Research
Molecular Formula C9H7NO4
Quantity 500 mg
Synonym NSC 170724 5-(2-Nitrovinyl)benzodioxole
Solubility Information DMSO : 50 mg/mL (258.85 mM; Need ultrasonic) ∣H2O : 0.67 mg/mL (3.47 mM; Need ultrasonic)
SMILES O=[N+]([O-])/C=C/C1=CC(OCO2)=C2C=C1
Molecular Weight (g/mol) 193.16
Formula Weight 193.16
Percent Purity 99.55%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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