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MK-886, MedChemExpress
Description
MK-886 (L 663536) is a potent, cell-permeable and orally active FLAP (IC50 of 30 nM) and leukotriene biosynthesis (IC50s of 3 nM and 1.1 μM in intact leukocytes and human whole blood, respectively) inhibitor. MK-886 is also a non-competitive PPARα antagonist and can induce apoptosis.
Specifications
Specifications
| Chemical Name or Material | MK-886 |
| CAS | 118414-82-7 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C27H34ClNO2S |
| Quantity | 25 mg |
| Synonym | L 663536 |
| Solubility Information | DMSO : 75 mg/mL (158.87 mM; Need ultrasonic) |
| SMILES | CC(C)C1=CC=C(N(CC2=CC=C(Cl)C=C2)C(CC(C)(C(O)=O)C)=C3SC(C)(C)C)C3=C1 |
| Molecular Weight (g/mol) | 472.08 |
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Research purposes only
Product Title
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