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  6. Mavorixafor trihydrochloride, MedChemExpress

Mavorixafor trihydrochloride, MedChemExpress

Product Code. 16493977
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Product Code. 16493977 Supplier Medchem Express Supplier No. HY50101A

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Description

MedChemExpress Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.

Mavorixafor trihydrochloride (AMD-070 trihydrochloride) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively.

Specifications

Chemical Name or Material Mavorixafor trihydrochloride
Physical Form Solid
CAS 2309699-17-8
Color Yellow
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C21H30Cl3N5
For Use With (Application) COVID-19-anti-virus
Synonym AMD-070 trihydrochloride
Solubility Information DMSO : 150 mg/mL (326.90 mM; Need ultrasonic) ∣H2O : 100 mg/mL (217.93 mM; Need ultrasonic)
SMILES [H]Cl.[H]Cl.[H]Cl.NCCCCN(CC1=NC2=CC=CC=C2N1)[C@@H]3C4=NC=CC=C4CCC3
Molecular Weight (g/mol) 458.86
Formula Weight 458.86
Percent Purity 98.0%
Grade Research
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