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  7. Luzindole, 97%, Thermo Scientific Chemicals

Luzindole, 97%, Thermo Scientific Chemicals

Product Code. 15404409
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Product Code. 15404409 Supplier Thermo Scientific Alfa Aesar Supplier No. J61915.#0
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Description

A melatonin receptor antagonist

Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Luzindole significantly antagonizes melatonin-mediated antinociception, suggesting that MEL-1B-R plays a further role as a mediator of melatonin modulation of pain signaling. It is used both in vitro and in vivo to evaluate the roles of melatonin receptor signaling in diverse pathways, including circadian rhythms, animal behavior, and melanophore response

Solubility
Soluble in DMSO (100 mM), ethanol (100 mM), chloroform, methanol, and water.

Notes
Protect from heat. Incompatible with heat and oxidizing agents. Store at 4°C.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 117946-91-5
Molecular Formula C19H20N2O
Molecular Weight (g/mol) 292.38
MDL Number MFCD00672498
InChI Key WVVXBPKOIZGVNS-UHFFFAOYSA-N
Synonym luzindole, n-acetyl-2-benzyltryptamine, 2-benzyl-n-acetyltryptamine, n-2-2-benzyl-1h-indol-3-yl ethyl acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl acetamide, tocris-0877, n-acetyl-2-benzyl-tryptamine, acetamide, n-2-2-phenylmethyl-1h-indol-3-yl ethyl, n-2-2-benzylindol-3-yl ethyl acetamide
PubChem CID 122162
IUPAC Name N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
SMILES CC(=O)NCCC1=C(CC2=CC=CC=C2)NC2=CC=CC=C12

Specifications

Melting Point 44°C to 46°C
Color White to Brown
Quantity 5 mg
Solubility Information Soluble in DMSO (100 mM),ethanol (100 mM),chloroform,methanol,and water.
Formula Weight 292.37
Percent Purity 97%
Physical Form Powder
Chemical Name or Material Luzindole

RUO – Research Use Only

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