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Lopinavir, MedChemExpress

Product Code. 16489855
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Product Code. 16489855

Brand: Medchem Express HY14588

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MedChemExpress Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM.

Lopinavir (ABT-378) is a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis of 1.3 to 3.6 pM for wild-type and mutant HIV protease. Lopinavir acts by arresting maturation of HIV-1 thereby blocking its infectivity. Lopinavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 14.2 μM.

Specifications

Chemical Name or Material Lopinavir
Physical Form Solid
CAS 192725-17-0
Color White
Quantity 250 mg
Purity Grade Notes Research
Molecular Formula C37H48N4O5
For Use With (Application) COVID-19-anti-virus
Synonym ABT-378
Solubility Information DMSO : 250 mg/mL (397.58 mM; Need ultrasonic)
SMILES CC1=C(OCC(N[C@@H](CC2=CC=CC=C2)[C@@H](O)C[C@H](CC3=CC=CC=C3)NC([C@H](C(C)C)N4C(NCCC4)=O)=O)=O)C(C)=CC=C1
Molecular Weight (g/mol) 628.8
Formula Weight 628.8
Percent Purity 99.81%
Grade Research
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