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Leukadherin-1, MedChemExpress

Product Code. 16446886
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Product Code. 16446886 Supplier Medchem Express Supplier No. HY15701

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Description

MedChemExpress Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.

Leukadherin-1, a specific agonist of the leukocyte surface integrin CD11b/CD18, increases CD11b/CD18-dependent cell adhesion to fibrinogen with an EC50 of 4 μM. Leukadherin-1 enhances leukocyte adhesion to ligands (such as ICAM-1) and vascular endothelium and thus reduces leukocyte transendothelial migration and influx to the injury sites. Leukadherin-1 suppresses innate inflammatory signaling.

Specifications

Chemical Name or Material Leukadherin-1
CAS 344897-95-6
Color Orange
Purity Grade Notes Research
Molecular Formula C22H15NO4S2
Quantity 100 mg
Solubility Information DMSO : 5 mg/mL (11.86 mM; Need ultrasonic)
SMILES O=C(O)C1=CC=C(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)C=C1
Molecular Weight (g/mol) 421.49
Formula Weight 421.49
Percent Purity 98.0%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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