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Leu-AMS, MedChemExpress

Product Code. 16431119
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Product Code. 16431119 Supplier Medchem Express Supplier No. HY108900

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Description

MedChemExpress Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria.

Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. Leu-AMS shows cytotoxicity in cancer cells and normal cells, and inhibits the growth of bacteria.

Specifications

Chemical Name or Material Leu-AMS
CAS 288591-93-5
Color White
Purity Grade Notes Research
Molecular Formula C16H25N7O7S
Quantity 1 mg
Solubility Information DMSO : ≥ 49.17 mg/mL (107.01 mM)
SMILES O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COS(=O)(NC([C@@H](N)CC(C)C)=O)=O
Molecular Weight (g/mol) 459.48
Formula Weight 459.48
Percent Purity 97.04%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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