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Tocris Bioscience™ Lestaurtinib

Product Code. 18045682
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Quantity:
1 mg
Unit Size:
1mg
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18045682 1 mg 1mg
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Product Code. 18045682 Supplier Tocris Bioscience™ Supplier No. 3395/1

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318.80 EUR valid until 2026-03-31
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Description

JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB

Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM, respectively). Also inhibits Aurora kinase A and B (IC50 values are 8.1 and 2.3 nM, respectively) and prevents STAT5 phosphorylation (IC50 = 20 - 30 nM). Exhibits antiproliferative activity in vitro (IC50 = 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo.
TRUSTED_SUSTAINABILITY

Specifications

CAS 111358-88-4
Quantity 1 mg
Molecular Formula C26H21N3O4
Formula Weight 439.46
Purity >99%
Molecular Weight (g/mol) 439.47
Chemical Name or Material Lestaurtinib
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