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Description
The progesterone receptor (PgR) is an estrogen-regulated protein. It has been proposed that expression of PgR determination indicates a responsive estrogen receptor (ER) pathway, and therefore, may predict likely response to endocrine therapy in human breast cancer. A number of studies have shown that PgR determination provides supplementary information to ER, both in predicting response to endocrine therapy and estimating survival. PgR has proved superior to ER as a prognostic indicator in some studies.
Host Species: Rabbit
Clone: SP2
Isotype: IgG
Species Reactivity: Human. Others not tested.
Epitope: 412-526aa
Immunogen: Recombinant protein encoding human progesterone receptor 412-526aa
Molecular Weight: 116 + 81kDa
Positive Control: Breast CA, T47D cells
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
Specifications
Specifications
| Antigen | Progesterone Receptor (SP2) |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | SP2 |
| Conjugate | Unconjugated |
| Host Species | Rabbit |
| Immunogen | Recombinant protein encoding human progesterone receptor 412-526 aa |
| Quantity | 7 mL |
| Regulatory Status | IVD |
| Research Discipline | Cancer and Tumor Biology |
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Product Title
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