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JH-VIII-157-02, MedChemExpress

Product Code. 16485426
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Product Code. 16485426 Supplier Medchem Express Supplier No. HY112140

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Description

MedChemExpress JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

JH-VIII-157-02 is a structural analogue of alectinib, acts as an ALK inhibitor, and shows an IC50 of 2 nM for echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) G1202R in cells.

Specifications

Chemical Name or Material JH-VIII-157-02
Physical Form Solid
CAS 1639422-97-1
Color Off-White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C28H27N5O2
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : ≥ 25 mg/mL (53.70 mM)
SMILES O=C(N(C)C)CN1N=CC(C2=C(CC)C=C3C(C(C)(C)C(NC4=C5C=CC(C#N)=C4)=C5C3=O)=C2)=C1
Molecular Weight (g/mol) 465.55
Formula Weight 465.55
Percent Purity 99.67%
Grade Research
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Research purposes only

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