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Ivermectin, Tocris Bioscience™

Description
Positive allosteric modulator of the α7 neuronal nicotinic acetylcholine receptor and the purinergic P2X4 receptor. Antihelmintic and antiviral. Also modulates glutamate- and GABA-activated chloride channels. Potentiates glycine-gated currents at low concentrations (30 nM). Inhibits replication of SARS-CoV-2 in vitro (IC50 ∽ 2μM).
This product is composed of both Ivermectin B1a (>90%) and Ivermectin B1b.
Specifications
Specifications
| CAS | 70288-86-7 |
| Molecular Formula | C48H74O14 |
| Quantity | 100 mg |
| Synonym | ivermectin |
| InChI Key | AZSNMRSAGSSBNP-RDKIRRGNSA-N |
| SMILES | CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C |
| Molecular Weight (g/mol) | 875.106 |
| PubChem CID | 122172888 |
| Formula Weight | 875.1 |
| Percent Purity | >96% |
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