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Ivacaftor, MedChemExpress

Product Code. 16468197
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Product Code. 16468197 Supplier Medchem Express Supplier No. HY13017

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MedChemExpress Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.

Ivacaftor (VX-770) is a potent and orally bioavailable CFTR potentiator, targeting G551D-CFTR and F508del-CFTR with EC50s of 100 nM and 25 nM, respectively.

Specifications

Chemical Name or Material Ivacaftor
CAS 873054-44-5
Color Off-White
Purity Grade Notes Research
Molecular Formula C24H28N2O3
Quantity 5 mg
Synonym VX-770
Solubility Information DMSO : 50 mg/mL (127.39 mM; Need ultrasonic)
SMILES CC(C)(C1=C(C=C(C(C(C)(C)C)=C1)O)NC(C2=CNC3=C(C2=O)C=CC=C3)=O)C
Molecular Weight (g/mol) 392.49
Formula Weight 392.49
Percent Purity 99.08%
Grade Research
Physical Form Solid
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