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  7. Thermo Scientific Chemicals Indomethacin

Thermo Scientific Chemicals Indomethacin

Código de producto. 15462202 Tienda Thermo Scientific Chemicals Productos
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    38.65 EUR / 5g
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Descripción

Indomethacin, CAS # 53-86-1, is an indole-based nonsteroidal anti-inflammatory (NSAID). | CAS: 53-86-1 | C19H16ClNO4 | 357.79 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Indomethacin is a synthetic NSAID of the indole family that inhibits cyclooxygenase and reduces prostaglandin and pyrogen release

• Indomethacin may suppress the multi-drug resistant transporter and thereby increase the efficacy of antineoplastics

• Indomethacin activates phosphatases that inhibit signaling pathways associated with cancer cell migration and proliferation

Applications

• Indomethacin may be used for the laboratory study of cancer cell proliferation, tumorigenesis and drug interactions

• Indomethacin may be used for laboratory study of the effect of inhibiting the multi-drug resistance transporter, or for downregulation of survival signaling in cells via survivin

TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 53-86-1
Molecular Formula C19H16ClNO4
Molecular Weight (g/mol) 357.79
InChI Key CGIGDMFJXJATDK-UHFFFAOYSA-N
Synonym indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
PubChem CID 3715
ChEBI CHEBI:49662
IUPAC Name 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Especificaciones

Melting Point 155.0°C
Loss on Drying 0.5% max. (100°C, 2 h, 5 mm Hg)
Infrared Spectrum Authentic
Quantity 5 g
Formula Weight 357.79
Percent Purity ≥97.5% (HPLC)
Chemical Name or Material Indomethacin

Seguridad y manipulación

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Nombre del producto
  • Indomethacin
 Palabra de advertencia
  • Danger
 Clasificación
  • Acute toxicity Category 1
  • Skin sensitiser Category 1
  • Reproductive toxicity Category 1B
 Indicaciones de peligro
  • H300-Fatal if swallowed.
  • H317-May cause an allergic skin reaction.
  • H360FD-May damage fertility. May damage the unborn child.
 Consejos de prudencia
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P330-Rinse mouth.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P201-Obtain special instructions before use.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.

RUO – Research Use Only

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