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Invitrogen™ Human IL-6 Matched Antibody Pair

Product Code. 15591677
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10 x 96 Tests
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15591677 10 x 96 Tests Pack of 10
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Product Code. 15591677 Supplier Invitrogen™ Supplier No. BMS2132MST
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    806.00 EUR
    620.62 EUR / Pack of 10
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Estimated Shipment: 10-08-2026
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Description

ELISA

The Human IL-6 Matched Antibody Pair Kit comes with pre-matched antibody pairs, standards, and streptavidin-HRP to develop your own enzyme linked immunosorbent assays (ELISA) to detect and quantify protein levels of human IL-6. Buffer reagents and microplates needed to complete the ELISA reaction are sold separately. Principle of the method ELISAs are designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody is coated to the bottom of the wells of a microplate, which is an overnight process. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. A sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.

IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P05231
Antigen IL-6
Assay Range 1.56-100 pg/mL
Applications ELISA
Assay Sensitivity 1.56 pg/mL
Classification Monoclonal
Conjugate Biotin, HRP
Gene Accession No. P05231
Gene Alias Interferon-beta 2, B-cell stimulatory factor 2,HGF, B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BSF2; BSF-2; CDF; CHIL-6; CTL differentiation factor; cytokine; HGF; H-IL-6; HSF; hybridoma growth factor; Ifnb2; IFN-beta-2; Il6; IL-6; ILg6; ILN; interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin 6 precursor; interleukin BSF-2; interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 precursor; interleukin-6 protein; M-IL-6; prointerleukin 6; R-IL-6; BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Gene Symbols IL6
Immunoassay Kit Format Matched Antibody Pair
Product Type ELISA, ELISA Kit
Quantity 10 x 96 Tests
Sample Type Plasma, Serum, Supernatant
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3569
Target Species Human
For Use With (Equipment) Absorbance Microplate Reader
Content And Storage -20°C
Gene Symbol Il6
Kit Contents Capture (coating) Antibody, Detection Antibody, SAV-HRP conjugate, Standard
Label or Dye Biotin
Storage Requirements -20°C
Target IL-6
Test Time 1 hr 10 min
Total Assay Time 24 hr
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