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  6. Invitrogen™ IL-28 (IFN lambda) Monoclonal Antibody (RN28), eBioscience™, Invitrogen™

Invitrogen™ IL-28 (IFN lambda) Monoclonal Antibody (RN28), eBioscience™, Invitrogen™
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Product Code. 15218057
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500 μg
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Product Code. 15218057 Supplier Invitrogen™ Supplier No. 14728181

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Description

Rat Monoclonal Antibody

Description: This monoclonal RN28 antibody reacts with IL-28 (IFN lambda), a member of the IFN-lambda family which mediates the induction of anti-viral protection in a wide variety of cells. Applications Reported: The RN28 antibody has been reported for use in ELISA capture of mouse IL-28. Applications Tested: This RN28 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse IL-28 in combination with the biotin polyclonal (cat. 13-7282) antibody for detection. A suitable range of concentrations of this antibody for ELISA capture is 1.0-4 μg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 4000 pg/mL - 30 pg/mL should be included in each ELISA plate. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 μm post-manufacturing filtered.

IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
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Specifications

Antigen IL-28 (IFN lambda)
Applications ELISA
Classification Monoclonal
Clone RN28
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene Ifnl3
Gene Accession No. Q4VK74, Q8CGK6
Gene Alias Cytokine Zcyto20; cytokine Zcyto22; EG330496; IFL-1; IFN lambda2; Ifnl2; Ifnl3; IFN-lambda2; IFN-lambda-2; IFN-lambda-3; IFN-lambda-4; IL 28; IL 28 A; Il28; Il28a; IL-28A; Il28b; IL-28B; IL28C; IL-28C; ILN; INF-alpha; INF-lambda; interferon alpha; interferon lambda 2; interferon lambda 3; Interferon lambda2; interferon lambda-2; Interferon lambda-3; interferon, lambda 2; interferon, lambda 3; interferon, lambda 4; interferon-lambda 2; interferon-lambda2; Interleukin; interleukin 28; interleukin 28A; interleukin 28A (interferon, lambda 2); interleukin 28B; interleukin-28A; Interleukin-28B; interleukin-28C; ZCYTO20; ZCYTO22
Gene Symbols Ifnl2, Ifnl3
Host Species Rat
Purification Method Affinity chromatography
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 330496, 338374
Target Species Mouse
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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