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Tocris™ HODHBt

Product Code. 18738416
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Quantity:
100 mg
Unit Size:
100mg
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Product Code. 18738416

Brand: Tocris™ 6994/100

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Description

STAT5-SUMO protein-protein interaction inhibitor

HODHBt is a STAT5-SUMO protein-protein interaction inhibitor. Blocks SUMOylation of phosphorylated STAT5. Reactivates latent HIV-1 reservoir in central memory T cells (TCM). Increases viral release by ~2.7-fold at a concentration of 100 μM in combination with IL-2 compared to unstimulated cells; reduces size of latent HIV-1 reservoir in vitro.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 3-Hydroxy-1,2,3-benzotriazin-4(3 H)-one
CAS 28230-32-2
Quantity 100 mg
Solubility Soluble to 100 mM in DMSO and to 50 mM in ethanol
Target Antiviral Compounds
Molecular Formula C7H5N3O2
Formula Weight 163.14
Product Type Inhibitor
Purity 98%
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