missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Pyrimidines And Derivatives
  7. HDACs/mTOR Inhibitor 1, MedChemExpress

HDACs/mTOR Inhibitor 1, MedChemExpress

Product Code. 16471087
Encompass_Preferred
Change view
Click to view available options
Quantity:
5 mg
10 mg
50 mg
100 mg
Unit Size:
100mg
10mg
50mg
5mg
4 product options available for selection
Product selection table with 4 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16471087 50 mg 50mg
16464828 10 mg 10mg
16457577 5 mg 5mg
16415626 100 mg 100mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 4 options available.
4 options
This item is not returnable. View return policy
Product Code. 16471087 Supplier Medchem Express Supplier No. HY114414

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo.

HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively. HDACs/mTOR Inhibitor 1 stimulates cell cycle arrest in G0/G1 phase and induce tumor cell apoptosis with low toxicity in vivo.

Specifications

Chemical Name or Material HDACs/mTOR Inhibitor 1
CAS 2271413-06-8
Color White
Purity Grade Notes Research
Molecular Formula C28H38N8O5
Quantity 50 mg
Solubility Information DMSO : 32.5 mg/mL (57.35 mM; Need ultrasonic)
SMILES O=C(NO)CCCCCCN1C2=NC(C3=CC=C(NC(N4C[C@@H](C)OCC4)=O)C=C3)=NC(N5CCOCC5)=C2C=N1
Molecular Weight (g/mol) 566.65
Formula Weight 566.65
Percent Purity 98.21%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neurodegeneration
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.