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GSK-690693, MedChemExpress

Product Code. 16453738
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Product Code. 16453738 Supplier Medchem Express Supplier No. HY1024910mg

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Description

MedChemExpress GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.

GSK-690693 is an ATP-competitive pan-Akt inhibitor with IC50s of 2 nM, 13 nM, 9 nM for Akt1, Akt2 and Akt3, respectively. GSK-690693 is also an AMPK inhibitor, affects Unc-51-like autophagy activating kinase 1 (ULK1) activity and robustly inhibits STING-dependent IRF3 activation.

Specifications

Chemical Name or Material GSK-690693
CAS 937174-76-0
Color Yellow
Purity Grade Notes Research
Molecular Formula C21H27N7O3
Quantity 10 mg
Solubility Information DMSO : 30 mg/mL (70.51 mM; Need ultrasonic) ∣H2O : 5 mg/mL (11.75 mM; ultrasonic and adjust pH to 5 with HCl)
SMILES CC(O)(C)C#CC1=NC=C(OC[C@@H]2CNCCC2)C3=C1N=C(C4=NON=C4N)N3CC
Molecular Weight (g/mol) 425.48
Formula Weight 425.48
Percent Purity 96.35%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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