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GNE-493, MedChemExpress

Product Code. 16454178
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Product Code. 16454178 Supplier Medchem Express Supplier No. HY10811

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Description

MedChemExpress GNE-493 is a potent, selective, and orally available dual pan-PI3-kinase/mTOR inhibitor with IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.

GNE-493 is a potent, selective, and orally available dual pan-PI3-kinase/mTOR inhibitor with IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR.

Specifications

Chemical Name or Material GNE-493
Physical Form Solid
CAS 1033735-94-2
Color Dust Gray
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C17H20N6O2S
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : ≥ 45 mg/mL (120.82 mM)
SMILES OC(C)(C)C1=CC2=C(S1)C(N3CCOCC3)=NC(C4=CN=C(N)N=C4)=N2
Molecular Weight (g/mol) 372.44
Formula Weight 372.44
Percent Purity 98.33%
Grade Research
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Research purposes only

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