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  6. Glutathione Reduced, Cell Culture Reagent, ≥98%, MP Biomedicals™

Glutathione Reduced, Cell Culture Reagent, ≥98%, MP Biomedicals™

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Product Code. 11455202

Brand: MP Biomedicals 0219467925

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Description

Glutathione Reduced, Cell Culture Reagent, ≥98% is used for protein purification and elutes GST-tagged protein from glutathione agarose.

  • Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells.
  • It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds.
  • Glutathione is an endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst.
  • Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center.
  • Glutathione also forms disulfide bonds with cysteine residues in proteins.
  • Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
  • Typical Working Concentration: May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 70-18-8
Molecular Formula C10H17N3O6S
Molecular Weight (g/mol) 307.321
MDL Number MFCD00065939
InChI Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Synonym glutathione, l-glutathione, glutathion, glutathione-sh, glutinal, isethion, tathion, reduced glutathione, deltathione, neuthion
PubChem CID 124886
ChEBI CHEBI:16856
IUPAC Name (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
SMILES C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N

Specifications

Melting Point 195°C
Color White
Assay Percent Range >98%
Quantity 25 g
Solubility Information 292.5 mg/mL
Formula Weight 307.32
Percent Purity ≥98%
Grade Cell Culture
Physical Form Powder
Chemical Name or Material Glutathione Reduced, Cell Culture Reagent

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use.

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