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Gefapixant, MedChemExpress

Product Code. 16493438
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Product Code. 16493438

Brand: Medchem Express HY101588

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Description

MedChemExpress Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ∼30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis.

Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ∼30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis.

Specifications

Chemical Name or Material Gefapixant
CAS 1015787-98-0
Color White
Purity Grade Notes Research
Molecular Formula C14H19N5O4S
Quantity 10 mg
Synonym MK-7264 AF-219
Solubility Information DMSO : 5 mg/mL (14.15 mM; ultrasonic and adjust pH to 5-6 with HCl)
SMILES O=S(C1=CC(OC2=CN=C(N)N=C2N)=C(C(C)C)C=C1OC)(N)=O
Molecular Weight (g/mol) 353.4
Formula Weight 353.4
Percent Purity 98.01%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-anti-virus
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Research purposes only

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