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Forskolin, 98+%

Product Code. 15435559
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Product Code. 15435559 Supplier Thermo Scientific Alfa Aesar Supplier No. J63292.MA
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Beschreibung

Forskolin, CAS # 66575-29-9, is a diterpenoid compound isolated from Indian Coleus that acts as a strong activator of the adenylate cyclase system. | CAS: 66575-29-9 | C22H34O7 | 410.507 g/mol

Forskolin acts as an adenylyl cyclase activator. It is used in the treatment of hypertension, asthma, eczema, psoriasis, congestive heart failure, angina, stomachache, gastric and intestinal spasm. It also plays an important role in the treatment of rheumatism, heart, blood and circulation conditions and cancers. It is used to induce menstruation and as an oral contraceptive.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Forskolin is a diterpenoid and cyclic ketone, found naturally as a plant metabolite

• It is a protein kinase A agonist and a cyclic ketone • Forskolin is an antihypertensive and muscle relaxant; it can also promote the release of pituitary hormones and prevent platelet aggregation

Application

• Forskolin assists in neuron differentiation in vitro

• Useful for studies of cell metabolism and development; there is some evidence of its usefulness in the study of glaucoma

• It is intended for cell culture and biochemistry applications

TRUSTED_SUSTAINABILITY

Chemische Identifikatoren

CAS 66575-29-9
Molecular Formula C22H34O7
Molecular Weight (g/mol) 410.507
MDL Number MFCD00082317
InChI Key OHCQJHSOBUTRHG-KGGHGJDLSA-N
Synonym forskolin, colforsin, coleonol, colforsina, colforsine, colforsinum, boforsin, colforsine french, colforsinum latin, colforsina spanish
PubChem CID 47936
ChEBI CHEBI:42471
IUPAC Name [(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-5,6,6a,8,9,10-hexahydro-2H-benzo[f]chromen-5-yl] acetate
SMILES CC(=O)OC1C(C2C(CCC(C2(C3(C1(OC(CC3=O)(C)C=C)C)O)C)O)(C)C)O

Spezifikation

Color White
Quantity 10 mg
Beilstein 1692716
Merck Index 14,2476
Solubility Information Soluble in ethanol,dimethylsulfoxide and chloroform; Insolule in water.
Formula Weight 410.51
Percent Purity ≥98%
Physical Form Solid
Chemical Name or Material Forskolin

RUO – Research Use Only

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