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Ethidium bromide soln., 10mg/ml
Beschreibung
Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids.1,2,3 It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA.4 Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. Ethidium bromide intercalates double-stranded DNA and RNA and acts as a frameshift mutagen. It can also be used in conjunction with acridine orange to differentiate between viable, apoptotic and necrotic cells.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Spezifikation
Spezifikation
| Color | Red |
| CAS | 1239-45-8 |
| Molecular Formula | C21H20BrN3 |
| MDL Number | MFCD00011724 |
| UN Number | UN2810 |
| Concentration | 10mg/ml |
| Merck Index | 14,4731 |
| Synonym | ethidium bromide, homidium bromide, dromilac, 3,8-diamino-5-ethyl-6-phenylphenanthridinium bromide, ethydium bromide, 3,8-diamino-5-ethyl-6-phenylphenanthridin-5-ium bromide, etbr, 2,7-diamino-10-ethyl-9-phenylphenanthridinium bromide, 2,7-diamino-9-phenyl-10-ethylphenanthridinium bromide, unii-059nuo2z1l |
| Solubility Information | Soluble in water (10mg/mL). |
| InChI Key | ZMMJGEGLRURXTF-UHFFFAOYSA-N |
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Sicherheit und Handhabung
- Ethidium bromide solution, 10 mg/ml
- Danger
- Acute toxicity Category 3
- Germ cell mutagenicity Category 2
- H331-Toxic if inhaled.
- H341-Suspected of causing genetic defects.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contain: 3,8-Diamino-1-ethyl-6-phenylphenantridinium bromide
RUO – Research Use Only
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