missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ DL-AP5 Sodium salt

Tocris Bioscience™ DL-AP5 Sodium salt
GREENER_CHOICE

Product Code. 18044332
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
This item is not returnable. View return policy

Product Code. 18044332

Brand: Tocris Bioscience™ 3693/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent and selective NMDA antagonist; sodium salt of DL-AP5

DL-AP5 Sodium salt is the sodium salt of DL-AP5 (Cat. No. 0105) and a racemic mixture of the D- and L-isomers of AP5, a selective NMDA receptor antagonist that competes with glutamate binding and is commonly used to inhibit NMDA-dependent synaptic plasticity. D-AP5 (Cat. No. 0106) is the more active isomer and displays approximately 52-fold higher potency than the L-isomer, L-AP5 (Cat. No. 0107). In vitro D-AP5 reduces NMDA-induced depolarization of cortical neurons, with no effect on the response to L-Quisqualic acid (Cat. No. 0188) or Kainic acid (Cat. No. 0222). Following spinal injection of D-AP5, NMDA-response is rapidly reduced, with no effect seen on spontaneously active neurons.

DL mixture, D-isomer and L-isomer also available.

TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type DL-AP5 Sodium salt
Purity >98%
Molecular Weight (g/mol) 219.11
Inhibitors DL-AP5 Sodium salt

For Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.