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Disulfiram, MedChemExpress

Product Code. 16490838
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5 g
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16442109 1 g 1g
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Product Code. 16490838 Supplier Medchem Express Supplier No. HYB0240

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Description

MedChemExpress Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.

Disulfiram inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells. Disulfiram + Cu2+ increases intracellular ROS levels triggering apoptosis of ovarian cancer stem cells[1-6].

Specifications

Chemical Name or Material Disulfiram
Physical Form Powder
CAS 97-77-8
Color Off-White
Quantity 5 g
Purity Grade Notes Research
Molecular Formula C10H20N2S4
For Use With (Application) Cancer-programmed cell death
Synonym Tetraethylthiuram disulfide TETD
Solubility Information DMSO : 75 mg/mL (252.92 mM; Need ultrasonic)
SMILES S=C(SSC(N(CC)CC)=S)N(CC)CC
Molecular Weight (g/mol) 296.54
Formula Weight 296.54
Percent Purity 98.0%
Grade Research
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Research purposes only

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