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Dexamethasone, 98%

Product Code. 11428217
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11428217 25 g 25g
11408217 1 g 1g
11418217 5 g 5g
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Product Code. 11428217 Supplier Thermo Scientific Alfa Aesar Supplier No. A17590.14
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Description

CAS: 50-02-2 | C22H29FO5 | 392.47 g/mol

Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Anti-inflammatory glucocorticoidDexamethasone is used to treat inflammatory and autoimmune conditions such as rheumatoid arthritis and bronchospasm. It is useful to study apoptosis, cell signaling pathways and gene expression. It is associated with marbofloxacin and clotrimazole and finds application in veterinary medicine to treat difficult ear infections in dogs. It is also used to treat horses with swelling of of distal limbs and general bruising in combination with trichlormethiazide. It is also an anti-inflammatory glucocorticoid.

Solubility
Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.

Notes
Store in cool place. Light sensitive. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 50-02-2
Molecular Formula C22H29FO5
Molecular Weight (g/mol) 392.47
MDL Number MFCD00064136
InChI Key UREBDLICKHMUKA-CXSFZGCWSA-N
Synonym dexamethasone, decadron, dexamethazone, maxidex, decaspray, desametasone, hexadecadrol, dexacort, dexasone, hexadrol
PubChem CID 5743
ChEBI CHEBI:41879
IUPAC Name (1R,2R,3aS,3bS,9aS,9bR,10S,11aS)-9b-fluoro-1,10-dihydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one
SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

Specifications

Melting Point ∼260°C (decomposition)
Assay Percent Range 0.98
Quantity 25 g
Beilstein 2066651
Sensitivity Light sensitive
Merck Index 142943
Solubility Information Soluble in ethanol and dimethyl sulfoxide. Insoluble in water.
Optical Rotation +75° (c=1 in Doxane)
Formula Weight 392.47
Percent Purity 98%
Chemical Name or Material Dexamethasone
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