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Dexamethasone 21-phosphate disodium salt, 98%, Thermo Scientific™
Dexamethasone 21-phosphate disodium salt, CAS # 2392-39-4, is a synthetic adrenal glucocorticoid with potent anti-inflammatory activity.
Brand: Thermo Scientific Alfa Aesar J64083.03
| Quantity | 1g |
|---|
This item is not returnable.
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Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
Dexamethasone 21-phosphate disodium salt is a sodium phosphate salt form of dexamethasone, considered to be a synthetic adrenal glucocorticoid with anti-inflammatory activity
Application
Dexamethasone 21-phosphate disodium salt binds to specific nuclear steroid receptors, interfering with NF-kB activation and apoptotic pathways
It acts as an inducer of apoptosis and inhibitor of the sodium phosphate symporter
It has been used as a positive control to study its effects on ocular shedding of herpes simplex virus type 1 in the induced reactivation and spontaneous shedding rabbit models
This compound is used to study its protective effects against cisplatin-induced ototoxicity in the inner ear of guinea pigs
Chemical Identifiers
| 2392-39-4 | |
| 516.41 | |
| PLCQGRYPOISRTQ-FCJDYXGNSA-L | |
| 16961 | |
| disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate |
| C22H28FNa2O8P | |
| MFCD00079105 | |
| dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron | |
| CHEBI:4462 | |
| CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] |
Specifications
| 2392-39-4 | |
| MFCD00079105 | |
| 6473066 | |
| dexamethasone sodium phosphate, dexamethasone 21-phosphate disodium salt, dalalone, dexadreson, dexagro, megacort, soldesam, spersadox, decdan, solu-decadron | |
| PLCQGRYPOISRTQ-FCJDYXGNSA-L | |
| disodium;[2-[(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate | |
| 16961 | |
| 516.4 | |
| Dexamethasone 21-phosphate disodium salt |
| C22H28FNa2O8P | |
| 1g | |
| 142943 | |
| Soluble in water. Slightly soluble in ethanol. Insoluble in dichloromethane. | |
| CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)COP(=O)([O-])[O-])O)C)O)F)C.[Na+].[Na+] | |
| 516.41 | |
| CHEBI:4462 | |
| 98% |
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