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Dehydronitrosonisoldipine, MedChemExpress

Product Code. 16470489
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Product Code. 16470489 Supplier Medchem Express Supplier No. HYZ0816

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Description

MedChemExpress Dehydronitrosonisoldipine, a derivative of Nisoldipine (HY-17402), is an irreversible and cell-permeant sterile alpha and TIR motif-containing 1 (SARM1) inhibitor.

Dehydronitrosonisoldipine acts mainly by blocking SARM1 activation but not its enzymatic activities. Dehydronitrosonisoldipine inhibits SARM1 and axon degenration (AxD) by covalently modifying cysteines, also inhibits the Vincristine-activated cADPR production in neurons. Dehydronitrosonisoldipine can be used for researching neurodegenerative disorders.

Specifications

Chemical Name or Material Dehydronitrosonisoldipine
CAS 87375-91-5
Color Green
Purity Grade Notes Research
Molecular Formula C20H22N2O5
Quantity 10 mg
Solubility Information DMSO : 100 mg/mL (269.98 mM; Need ultrasonic)
SMILES O=C(C1=C(C2=CC=CC=C2N=O)C(C(OCC(C)C)=O)=C(C)N=C1C)OC
Molecular Weight (g/mol) 370.4
Formula Weight 370.4
Percent Purity 98.0%
Grade Research
Physical Form Solid
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Research purposes only

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